Current Management of Nasal NK/T-cell Lymphoma
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چکیده
Nasal natural killer (NK)/T-cell lymphoma is a unique type of non-Hodgkin lymphoma (NHL) that is almost always associated with Epstein-Barr virus (EBV). The disease predominantly localizes to the upper aerodigestive tract, most commonly in the nose. It is locally angioinvasive and destructive and was previously called lethal midline granuloma. However, up to 25% of patients have primary extranasal disease, without any apparent antecedent or concomitant nasal involvement by radiology, clinical examination, or biopsy.[1] Both categories are grouped together as extranodal NK/T-cell lymphoma (ENKTL), nasal type, in the World Health Organization (WHO) classification.[2]
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